Hemodynamic conditions of patient-specific carotid bifurcation based on ultrasound imaging Corresponding author:

نویسندگان

  • Luísa C. Sousa
  • Roberto Frias
  • Catarina F. Castro
  • Carlos C. António
  • André Miguel F. Santos
  • Rosa Maria dos Santos
  • Hernâni Monteiro
  • Pedro Miguel A. C. Castro
  • Elsa Azevedo
  • João Manuel R. S. Tavares
چکیده

The purpose of this paper is to complement the characterization of patient-specific carotid artery bifurcation hemodynamics based on image data obtained by Doppler ultrasound imaging. A methodology for patient-specific 3D luminal surface reconstruction followed by structured hexahedral meshing of the volume and blood flow simulation is presented. Quantitative descriptors of the flow based on wall shear stress (WSS) are used to compare healthy and stenosed carotid bifurcation hemodynamic disturbances. Independently on the presence of stenosis, the internal carotid artery has been identified as a region of abnormal high values of oscillating shear index and relative residence time, and low values of time averaged-WSS. For the healthy carotid bifurcation, WSS descriptors manage to capture flow disturbances at the external carotid artery. This work addresses the lack of quantitative analysis on anatomically realistic stenosed carotid bifurcations.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Evaluation of the Effect of Simplified and Patient-specific Arterial Geometry on Hemodynamic Flow in Stenosed Carotid Bifurcation Arteries

Numerous CFD studies have been performed on the motivation to elucidate the role of hemodynamic forces in the development of atherosclerosis in the coronary arteries and the carotid bifurcation artery. In order to improve CFD predictions, and to consider CFD as a clinical diagnostic or treatment planning tool, there is a need to ensure its accuracy and reliability through a systematic approach ...

متن کامل

Proposition of an outflow boundary approach for carotid artery stenosis CFD simulation.

The purpose of this study was to propose an innovative approach of setting outlet boundary conditions for the computational fluid dynamics (CFD) simulation of human common carotid arteries (CCAs) bifurcation based on the concept of energy loss minimisation at flow bifurcation. Comparisons between this new approach and previously reported boundary conditions were also made. The results showed th...

متن کامل

Advantages and pitfalls of three-dimensional ultrasound imaging of carotid bifurcation.

OBJECTIVES Several specialists use three-dimensional (3D) ultrasound as adjuvant imaging technique in their clinical practice. It has been applied to study carotid plaque morphology, surface and volume during atherosclerosis progression. Nonetheless, no papers have so far described the use of this technique in conditions different than carotid stenosis, such as bifurcation anatomy changes of th...

متن کامل

Geometric Characterization of the Normal and Mildly Diseased Human Carotid Bifurcation

INTRODUCTION The geometry of the carotid bifurcation has been proposed as a possible risk factor for atherosclerosis, by virtue of the purported role of local hemodynamics in early stages of atherosclerotic plaque development [1]. In this context it is of interest to study asymptomatic subjects with mild carotid artery disease. Instead, investigations of carotid bifurcation geometry and hemodyn...

متن کامل

Computer Simulation of Stenotic Carotid Bifurcations Hemodynamic and Ultrasonography

The carotid sinus of the carotid artery (CA) bifurcation is one of the favored sites for the genesis and development of atherosclerotic lesions. The direct reason is carotid arteries bifurcation and stenoses may lead to great flow pattern change. Aim of this article is to investigate the effect of different eccentric stenosis of internal carotid artery on blood flow. The blood flow in artery is...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2014